The college football season is into the final weeks of the year, as teams jockey for playoff seeding and postseason qualification. The expanded 12-team playoff was a great success last year, and it has added extra intensity to the college football predictions week 13 in the closing weeks of the year.The NCAAF odds have been released, the stakes couldn’t be higher, and there has never been a better time to head to your sportsbook and make free college football predictions.
College Football Week 13 Odds
The tensions are rising heading into week 13, and the razor-tight NCAAF odds further hammer home that fact. Teams are battling for the playoffs, players are fighting hard for their NFL draft stock, and there are several tantalizing matchups this week.
Before making free college football predictions on your social sportsbook, make sure you comb over the expert picks provided and carefully scan the American football odds to put yourself in the best position to come out on top.
| Matchup | Spread | Moneyline | Over/Under |
| Rutgers at Ohio State | Ohio State -31.5 (-120) | Rutgers +900 | 55.5 |
| Missouri at Oklahoma | Oklahoma -7.5 (-120) | MISS +220/OK -350 | 42.5 |
| Louisville at SMU | SMU -2.5 (-125) | LOU +105/SMU -150 | 48.5 |
| Miami at Virginia Tech | Miami -17.5 (-125) | MIA -1200/VT +500 | 48.5 |
| Charlotte vs Georgia | Georgia -43.5 (-120) | Charlotte +1000 | 53.5 |
| Syracuse at Notre Dame | Notre Dame -35.5 (-120) | Syracuse +1000 | 50.5 |
| USC at Oregon | Oregon -9.5 (-125) | USC +260/ORE -425 | 59.5 |
| Arkansas at Texas | Texas -9.5 (-115) | ARK +230/TEX -375 | 57.5 |
| Kentucky at Vanderbilt | Vanderbilt -9.5 (-120) | UK +260/VAND -425 | 53.5 |
| Tulane at Temple | Tulane -8.5 (-115) | TUL -375/TEMP +230 | 55.5 |
| TCU at Houston | Houston -1.5 (-110) | TCU -115/HOU -125 | 55.5 |
| Michigan at Maryland | Michigan -13.5 (-125) | MICH -650/MAR +350 | 45.5 |
| BYU at Cincinnati | BYU -2.5 (-120) | BYU -150/CIN +105 | 54.5 |
College Football Week 13 Odds Analysis

(#22) Missouri at (#8) Oklahoma
- Spread: Missouri +7.5, Oklahoma -7.5
- Moneyline: Missouri +220, Oklahoma -350
- Over/Under: 42.5 Points
- Time: Saturday, November 22nd, 12:00 PM EST
This one will be short and sweet. The Oklahoma Sooners are coming off back-to-back wins against Tennessee and Alabama, making this their easiest game in a month.
Across the field, Missouri has lost to all three ranked opponents they have played this year, with the most recent defeat coming by a 38-17 scoreline against Texas A&M. Missouri has the capability to keep pace with lower-tier college football teams, but it struggles against legitimate contenders.
Oklahoma certainly falls into the second category, and a double-digit win is on the cards in week 13. Don’t bother touching the moneyline on your sportsbook, as the college football odds on the point spread are a much better pick to make—and watching how the live Sports odds react early can help confirm that angle.
Pick: Oklahoma -7.5 (-120)YOU MIGHT ALSO LIKE: College Football Prediction Week 12
(#15) USC at (#7) Oregon
- Spread: USC +9.5, Oregon -9.5
- Moneyline: USC +260, Oregon -425
- Over/Under: 59.5 Points
- Time: Saturday, November 22nd, 3:30 PM EST
This is going to be a track meet from the opening kickoff, and the best college football week 13 prediction you can make is on the over.
USC
USC has a truly electric offense coupled with a struggling defense, which is the perfect recipe for an over. They like to play at a fast pace on offense, they’ll get aggressive on fourth down, and they will not change their identity against the mighty Oregon Ducks.
Even against the worst teams in the nation, USC has allowed at least two touchdowns in every game this season, and there is no doubt the Ducks will find the end zone on multiple occasions in this one. As long as the USC offense led by Jayden Maiava can do its part, 60+ points shouldn’t be too much to ask in this one.
Oregon
The Ducks, meanwhile, have scored 30+ points in 7 of 10 games this season and will be desperate to make a statement. Their wins have aged poorly, as they don’t have any victories over ranked opponents, and they need a statement victory against USC if they hope to sneak into the top 4.
Dante Moore is capable of running up the scoreboard, and a USC team that has struggled against the pass is the perfect victim for the talented signal caller. This will be a back-and-forth contest where the Ducks never take their foot off the gas on offense, and 40+ from the home team alone is a very realistic NCAAF prediction for this week.
Pick: Over 59.5 Points (-120)
College Football Week 13 Odds FAQ
When do College Football Week 13 games begin?
The college football week 13 games have already begun, but no ranked teams are playing in the midweek games. Florida State plays on Friday night, and a convincing win could get them one step closer to the ranking in the tail end of the season.
However, the college football games featuring ranked teams don’t begin until Saturday, November 22nd at Noon EST.
What is the Best Game this Week?
There are two ranked vs. ranked matchups this week, but the best game is Oregon vs. USC. This will be a close game between two teams, with the loser likely missing the college football playoffs.
Oregon is still searching for its first NCAA championship, and a home loss against USC would send them plummeting down the rankings with a weak strength of schedule. If you are only going to make college football week 13 predictions for one game, this is the one to do so, no matter which sportsbook you use.






