The Minnesota Twins will take a trip out West to face off against the Los Angeles Dodgers for this fascinating midweek series. The MLB odds have made it clear they expect the Dodgers to take the series in what could be a sweep. However, it is not as if the Dodgers have been playing dominant baseball. Los Angeles is 2-8 across their last 10 games, and their lead at the top of the NL West is no longer comfortable. Meanwhile, the Twins are fighting tooth and nail for an American League Wild Card spot with a 48-51 record. There is plenty to play for in this midweek series, and the baseball odds indicate there could be an upset or two brewing. Will the Dodgers finally snap out of their funk, or can the Twins pile on more misery in Los Angeles? Here are your expert MLB predictions and picks to find out.
Series Introduction:
- Teams: Minnesota Twins at Los Angeles Dodgers
- Dates: Monday, Tuesday, and Wednesday, July 21st-23rd, 2025
- First Pitch Times: 10:10 PM EST on Monday and Tuesday, 4:10 PM EST on Wednesday
- Venue: Dodger Stadium in Los Angeles, California
Series Preview:
This series may not have any head-to-head implications at the season’s end, but there is no shortage of tangible results for these clubs. The Dodgers have the most expensive payroll in the league, and anything short of a pennant would be seen as a huge disappointment. The Twins aren’t the most difficult team to welcome the Dodger Stadium, meaning Los Angeles has a real chance to get back on track against Minnesota. They are fresh off getting swept by the lowly Brewers, while the Twins dropped their first series after the All-Star break 2-1 to the Colorado Rockies.
Head-to-Head:
This has been a one-sided head-to-head series over the years, with the Dodgers being especially dominant in the last decade. The Twins took a 9-7 series lead to kick off this rivalry, but the Dodgers then won 11 straight meetings to go 14-2 against Minnesota over the last ten years. That includes a complete 15-0 demolition in Minnesota. The Twins have been no match for Los Angeles as of late, but they have a chance to right their wrongs as they take on an ice-cold Los Angeles team.
check out our full Arizona Diamondbacks vs Houston Astros Prediction analysis
Key Stats and Facts:
The Los Angeles Dodgers are in a massive funk, but a home stand against the Diamondbacks gives them a real chance to break out of their slump. The Dodgers’ lead on top of the NL West has shrunk to 3.5 games after they went 2-8 in their last 10 games. They have a 33-20 home record compared to just 25-22 on the road.
On the other hand, the Minnesota Twins have also been vastly different based on the venue. Their 20-31 road record has dented their playoff hopes this season, but there is still plenty of baseball left to be played. Byron Buxton has been their most consistent hitter, regardless of the ballpark the Twins suit up in. His 22 home runs, 57 RBIs, 17 stolen bases, and .289 average are all team highs. Minnesota will need a big game from its leadoff hitter if it expects to defy the MLB odds and make a late-season playoff push.
Predicted Lineups:

The Los Angeles Dodgers have the highest payroll in the MLB and have the privilege of putting out a truly stacked batting order and lineup on a nightly basis. The Twins are no slouches themselves, and certainly have the chance to upset the MLB odds with a few clutch hits. While nothing is guaranteed in the MLB, these are the usual lineups these two teams roll with on a nightly basis.
Minnesota Twins Predicted Batting Order and Lineup:
- 1: Byron Buxton
- 2: Willi Castro
- 3: Trevor Larnach
- 4: Ryan Jeffers
- 5: Carlos Correa
- 6: Brooks Lee
- 7: Matt Walner
- 8: Royce Lewis
- 9: Kody Clemens
Los Angeles Dodgers Predicted Batting Order and Lineup:
- 1: Shohei Ohtani
- 2: Mookie Betts
- 3: Freddie Freeman
- 4: Will Smith
- 5: Teoscar Hernandez
- 6: Andy Pages
- 7: Michael Conforto
- 8: Tommy Edman
- 9: Hyeseong Kim
Tips and Score Prediction:
The Los Angeles Dodgers are big favorites on the baseball odds, and it may be the time to ‘buy the dip’ on their poor form. Los Angeles is simply too talented both in the batter’s box and on the mound to continue their slump. The Minnesota Twins are a below-average MLB team that struggles on the road. Los Angeles will likely have a steep moneyline on the MLB odds, so the sharper pick to make is to take the run line on your sportsbook.
Final Thoughts:
The vibes are low in Los Angeles right now, but that is the nature of the 162-game MLB season. This is a talented team that is relatively healthy, and these down stretches will happen. A visit from the subpar Twins will be exactly what the doctor ordered, and there will be at least one big blowout in this series. Taking an alternative line on your sportsbook could be the way to go, depending on the MLB odds, as this series will not be competitive for long stretches.




