Serie A Predictions 2025

Serie A 2025 finale 🎯 Title deciders, European spots, and relegation battles—get comprehensive predictions today on Sportzino!

Alistair Corp

Updated on April 26, 2025

Serie A Predictions

After last weekend’s fixtures were postponed, a highly dramatic title race and pursuit of European places will resume in Serie A this weekend, with exciting fixtures around the country. While Inter Milan and Napoli continue their incredible fight atop the table, there’s a ton of drama below the pair in the table.

As many as nine teams are still in the mix for qualification in either the UEFA Champions League or UEFA Europa League, with giants Juventus clinging to the final Champions League spot with five games to go. 

Ahead of another round of fixtures, check out Sportzino’s Serie A predictions and Serie A odds.

Serie A Odds

MatchupDouble ChanceMoneylineOver/Under
Como vs. Genoa Como or draw (-500) 
Como or Genoa (-334)
Genoa or draw (-125)
Como (-119) / Draw (+233) / Genoa (+320)Over 2.5 (+120) / Under 2.5 (-167)
Venezia vs. AC MilanVenezia or draw (-105)
Venezia or AC Milan (-400)
AC Milan or draw (-567)
Venezia (+350) / Draw (+300) / AC Milan (-155)Over 2.5 (-143) / Under 2.5 (+105)
Fiorentina vs. EmpoliFiorentina or draw (-550)
Fiorentina or Empoli (-367)
Empoli or draw (-113)
Fiorentina (-134) / Draw (+250) / Empoli (+350)Over 2.5 (+110) / Under 2.5 (-150)
Inter Milan vs. AS RomaInter Milan or draw (-550)
Inter Milan or Roma (-375)
AS Roma or draw (-110)
Inter Milan (-137) / Draw (+266) / AS Roma (+333)Over 2.5 (-112) / Under 2.5 (+105)
Juventus vs. MonzaJuventus or draw (OTB)
Juventus or Monza (-1,100)
Monza or draw (+266)
Juventus (-550) / Draw (+500) / Monza (+1,400)Over 2.5 (-180) / Under 2.5 (+128)
Atalanta vs. LecceAtalanta or draw (-2,000)
Atalanta or Lecce (-800)
Lecce or draw (+214)
Atalanta (-434) / Draw (+466) / Lecce (+1,000)Over 2.5 (-180) / Under 2.5 (+128)
Napoli vs. TorinoNapoli or draw (-1,000)
Napoli or Torino (-550)
Torino or draw (+145)
Napoli (-240) / Draw (+320) / Torino (+650)Over 2.5 (-106) / Under 2.5 (-134)
Udinese vs. Bologna FCUdinese or draw (-123)
Udinese or Bologna FC (-350)
Bologna FC or draw (-500)
Udinese (+333) / Draw (+225) / Bologna FC (-123)Over 2.5 (+120) / Under 2.5 (-167)
Lazio vs. ParmaLazio or draw (-800)
Lazio or Parma (-500)
Parma or draw (+130)
Lazio (-213) / Draw (+320) / Parma (+475)Over 2.5 (-143) / Under 2.5 (+105)
Verona vs. CagliariVerona or draw (-300)
Verona or Cagliari (-250)
Cagliari or draw (-225)
Verona (+154) / Draw (+166) / Cagliari (+210)Over 2.5 (+140) / Under 2.5 (-200)

Serie A Predictions

Venezia vs. AC Milan

  • Double Chance: Venezia or draw (-105) / Venezia or AC Milan (-400) / AC Milan or draw (-567)
  • Moneyline: Venezia (+350) / Draw (+300) / AC Milan (-155)
  • Over/Under: Over 2.5 (-143) / Under 2.5 (+105)
  • Time: Sunday, April 27 at 6:30 a.m. ET 

It’s been far from a good season for Milan, who sit ninth in the Serie A table and out of reach of the European places at the moment. But, they have a great chance to pick up three points this weekend, as they face 18th place Venezia. 

Home hasn’t been particularly kind to Venezia this season, either, with the relegation-bound side averaging just 1.06 points per match at home. Milan, meanwhile, have been quite strong away from the San Siro, with an average of 1.44 points per match away. After a loss to Atalanta last weekend, expect Milan to bounce back.    

Pick: AC Milan (-155)

Inter Milan vs. AS Roma

  • Double Chance: Inter Milan or draw (-550) / Inter Milan or Roma (-375) / AS Roma or draw (-110)
  • Moneyline: Inter Milan (-137) / Draw (+266) / AS Roma (+333)
  • Over/Under: Over 2.5 (-112) / Under 2.5 (+105)
  • Time: Sunday, April 27 at 9:00 a.m. ET

Serie A leaders Inter Milan will host a surging challenger for Europe this weekend, as AS Roma visit the San Siro. Inter, atop the Serie A table on goal difference, need to rebound after a defeat at the hands of Bologna last weekend, while Roma are unbeaten in five.

Despite Roma’s recent surge, to get Inter at a good value here is a pick we must make. In the confines of the San Siro this season, Inter have lost just once and dropped points on three other occasions, averaging 2.44 points per home match. Against a Roma side that averages fewer than 1.4 points per match away, we trust Inter to take all three points.   

Pick: Inter Milan (-137)

Juventus vs. Monza

  • Double Chance: Juventus or draw (OTB) / Juventus or Monza (-1,100) / Monza or draw (+266)
  • Moneyline: Juventus (-550) / Draw (+500) / Monza (+1,400)
  • Over/Under: Over 2.5 (-180) / Under 2.5 (+128)
  • Time: Sunday, April 27 at 12:00 p.m. ET 

Amid a difficult season that may end with them outside of the European places, Juventus gets a gift on Sunday in the form of last place Monza. Though Juve have won just two of their previous five matches, they’re a far cry from struggling Monza, who have lost four in a row. 

Monza concedes an average of nearly 2.0 goals per game, and more than 2.0 goals per game away from home. They now have to travel to face a Juve team that scores an average of 1.6 goals per game at home. We’re happy to take the over here, and Juve might hit it by themselves.   

Pick: Over 2.5 (-180)

Napoli vs. Torino

  • Double Chance: Napoli or draw (-1,000) / Napoli or Torino (-550) / Torino or draw (+145)
  • Moneyline: Napoli (-240) / Draw (+320) / Torino (+650)
  • Over/Under: Over 2.5 (-106) / Under 2.5 (-134)
  • Time: Sunday, April 27 at 2:45 p.m. ET

The other Serie A title challenger will be playing in the south of Italy on Sunday, as second place Napoli host 10th place Torino. Napoli have been in great form lately, with three wins in their last four matches. Torino, too, have enjoyed a good stretch with a single loss across their last five games. 

Though Napoli have great home form, dropping points just four times all season at home, they face a difficult test on Sunday. Going back to the end of December, Torino have only lost twice. In the cauldron of Napoli’s home stadium, expect these sides to split the points.    

Pick: Draw (+320)

Serie A Predictions FAQ

When do the Serie A games begin?

The Serie A slate this weekend starts on Friday, April 25 at 2:45 p.m. ET. Atalanta and Lecce will get us underway with their kickoff on Friday afternoon. Sunday’s slate of matches will get underway with a pair of matches: Venezia hosts AC Milan, and Como plays host to Genoa at 6:30 a.m. ET on Sunday, April 27. The week’s fixtures come to a close on Monday, with a trio of matches including Hellas Verona hosting Cagliari at 2:45 p.m. ET.  

What is the best game on this week?

There are a few candidates for the best game of the week, but the crown has to go to the matchup in Milan, involving a title challenger. Inter Milan, atop the table but level on points with Napoli, host Roma in a match with huge implications for both sides.

How to Make Serie A predictions

Ready to make picks on the Serie A slate this weekend? Make sure to head over to Sportzino.com, where you can find every Serie A match on the schedule this week, and so much more!

About Author

Alistair Corp

Full Name: Alistair Corp.

Position: Sports Writer.

Bio

Alistair's covered sports professionally for the last nine years, including four years on an NFL beat. He's spent several years in the iGaming space and writes about sports ranging from the NFL to F1.

Experience

  • Copywriter — August 2024 — Present.
  • Managing Editor — May 2023 — June 2024.
  • Publishing Editor— January 2021 — May 2023.
  • Deputy Editor — May 2015 — January 2021.

Education

Alistair graduated with a Bachelor of Arts in English and a minor in Journalism and Publishing.

What helps Alistair Corp be up to date?

Though I don't use social media, I stay up to date through most mediums. I am a frequent reader of both national and local reporters. Additionally, I have a steady rotation of podcasts and videos that I lean on to keep me well informed. In sports handicapping and beyond, the best thing someone can do is know what they don't know. Sports, and predictions, are such dynamic areas that to feel you have gotten on top of a subject is to fall behind.

FAQ

  1. Do you have a favorite type of casino game or sports event you enjoy writing about?

    The NFL is what I enjoy covering the most, and it's what I have spent the majority of my career in. I have also been lucky enough to cover the rest of the major North American sports/leagues. For the 2022 and '23 Formula 1 seasons, I worked as a sports-betting content creator covering the championship.

  2. What advice would you give to someone new to sports predicting?

    Be aware of what you don't know.

  3. How do you stay up-to-date with the latest trends and developments in sports?

    Daily consumption of articles, videos, and podcasts.

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