The Dallas Cowboys and Kansas City Chiefs square off in what promises to be an excellent matchup on Thanksgiving. Dallas is coming off a big win against the Raiders to keep their playoff hopes alive, while the 5-5 Chiefs will be desperate to secure a victory.
Kansas City has yet to miss the playoffs in Patrick Mahomes’ tenure as the starting quarterback, but the NFL odds imply that is far from a sure thing this season.
Meanwhile, the Dallas Cowboys have been one of the highest scoring teams in the NFL this year, making an NFL prediction on the over a tantalizing proposition. Will the Cowboys be able to defend their home field and upset the NFL odds, or will the Kansas City Chiefs get one step closer to the postseason?
Let’s jump right into your expert Cowboys vs Chiefs predictions to find out.
Matchup: Cowboys vs Chiefs Overview
- Teams: Kansas City Chiefs at Dallas Cowboys
- Date: Thursday, November 27th, 2025
- Time: Kickoff is at 4:25 PM EST
- Venue: AT&T Stadium in Dallas, Texas
Current Cowboys vs Chiefs Odds:
| Kansas City Chiefs | Dallas Cowboys | |
| Moneyline | -240 | +170 |
| Spread | -5 (-120) | +5 (-120) |
| Total | Over 47.5 Points (-120) | Under 47.5 Points (-120) |
The NFL odds have disregarded home-field advantage and have made the Kansas City Chiefs sizable road favorites. Kansas City has the far superior defense compared to the Cowboys, and it is no surprise to see them in the favorite role.
On the other hand, Dallas has been a reliable NFL prediction at home this season, and their juicy moneyline odds make them a tempting prediction for this specific matchup.
The total points are set at 47.5 on the American football odds across all sportsbooks.
Why the Kansas City Chiefs Can Cover
The Kansas City Chiefs play complementary football, and the same can’t be said for the Dallas Cowboys.
The Chiefs have reached three straight Super Bowls on the back of strong defensive play, and they will need more of the same when they make the trip to Dallas. Kansas City has been excellent at stopping both the pass and the run, and they will undoubtedly be tested with Dak Prescott’s deep ball on Thanksgiving.
However, if they can shut down the likes of Lamar Jackson and Jared Goff, containing Dak Prescott is certainly within their reach.
While defense is undoubtedly crucial, the Chiefs will need Patrick Mahomes and the Kansas City offense to deliver if they hope to cover the spread, especially for anyone crafting an NFL prediction on this matchup.
Mahomes has looked like a shadow of his former self this season, and a struggling run game has amplified his shortcomings. Isaiah Pacheco has been hurt, Kareem Hunt is past his prime, and the Chiefs haven’t been able to establish the run in the last few weeks.
The biggest question mark heading into this game is the Dallas defense. They are still a below-average unit this season, and we didn’t learn too much from their shutdown against Geno Smith and the lowly Raiders in Week 11.
As long as the Chiefs can take care of business on defense, the two-time NFL MVP Mahomes will be able to do enough on offense to get this win and cover.
Why the Dallas Cowboys Can Cover
Dallas has their defensive shortcomings, but there isn’t a better offense in the league heading into this matchup.
CeeDee Lamb and George Pickens are two of the best receivers in the game, and Dak Prescott hasn’t hesitated to feed them early and often. Their benching in Las Vegas was short-lived, and both found the end zone for the second consecutive week.
The Cowboys have the league’s most explosive pass offense with 258 yards per game through the air, and that will not be slowing down anytime soon. Dallas has been able to outscore their defensive issues so far this season, but that strategy doesn’t work against the best teams in the league.
Kansas City is no slouch on either side of the ball, and the Cowboys will need to deliver on defense if they hope to cover the spread, let alone win outright. That said, the Cowboys are sizable underdogs on the NFL odds, and taking them to cover the spread is one of the best Cowboys vs Chiefs predictions you can make.
This is an incredible offense that will always be a threat to secure a backdoor cover, and they will cover the spread if this game is even remotely close in the fourth quarter.
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How to Make Kansas City Chiefs vs Dallas Cowboys Picks
The best way to make Kansas City Chiefs vs Dallas Cowboys picks is by visiting Sportzino.
Sportzino offers the best NFL odds for all three Thanksgiving Day matchups, and is the best place to make free NFL predictions. The free social sportsbook offers spreads, moneylines, totals, and countless player props for not only this matchup but every NFL game this season.
If you are looking for the best place to make free NFL predictions, look no further, as Sportzino has you covered this Thanksgiving.
