The Philadelphia Eagles have the privilege of opening up the NFL season after their Super Bowl victory last year, and they will be hosting their NFC East rivals, the Dallas Cowboys. Philadelphia was one of the most consistent NFL predictions you could have made last season, as they cruised to the top of the division and went a perfect 4-0 in the postseason. The story could not have been more different for the Cowboys, who had one of their most disappointing seasons in recent memory. However, week one of a new NFL season always brings optimism around the league, and both of these historic franchises will hope to get off to a good start. Will Dak Prescott and company play spoiler, or will the party start for the Eagles fanbase as they look to go back-to-back?
Matchup: Eagles vs Cowboys Overview
- Teams: Dallas Cowboys at Philadelphia Eagles
- Date: Thursday, September 4th, 2025
- Time: Kick-off is at 8:20 PM EST
- Venue: Lincoln Financial Field in Philadelphia, Pennsylvania
Current Eagles vs Cowboys Odds
| Philadelphia Eagles | Dallas Cowboys | |
| Moneyline | -320 | +220 |
| Spread | -7 (-120) | +7 (-120) |
The NFL odds have given the Philadelphia Eagles a significant advantage in the season’s first game. They are sizable favorites on both the moneyline and spread for the start of the 2025-2026 NFL season. Jalen Hurts is fresh off a Super Bowl victory and Super Bowl MVP award, and he will feel confident he can outduel a revitalized Dak Prescott. Dallas made significant upgrades to their offense, and will certainly believe they can win and send a message that they are not to be overlooked this season. As a result, the total points are up at 46.5, as both teams are expected to find the end zone on multiple occasions.
| Over 46.5 Points | Under 46.5 Points |
| -120 | -120 |
Expert Prediction: Who Wins?
Why the Philadelphia Eagles Can Win
The Philadelphia Eagles are fresh off their Super Bowl victory, and there is no doubt they are the better team on paper. They have the talent they need on both sides of the ball, and the addition of home-field advantage has made them significant favorites on the NFL odds. Their dominant defense held the Kansas City Chiefs off the scoresheet for more than half the Super Bowl last season, and they will feel confident they can stifle a talented Cowboys offense in this matchup.
Philadelphia fully understands the importance of winning the NFC East, and a divisional win to kick off the season could make this a game they look back on at the end of the season. They have the best running back in the league with Saquon Barkley, and the Cowboys have consistently struggled to slow down dominant backs. Barkley tore the Cowboys apart on the ground in their last meeting, and if he can even come close to his 167 rushing yards, this will be the Eagles game to lose.
One man who has not gotten enough credit in Philadelphia is quarterback Jalen Hurts. Hurts is one of the most physical quarterbacks in the league, and his ability to pick up tough yards often goes unnoticed. Hurts can be accurate when he has adequate pass protection, and shutting down the potent Cowboys pass rushers will be the Eagles top priority. If Philadelphia can control the game on offense and stay ahead of the sticks, they will pick up right where they left off with a week one victory over the Dallas Cowboys.
For more insights, see our DC Defenders vs St. Louis Battlehawks Predictions breakdown.
Why the Dallas Cowboys Can Win
There is no denying the fact that the Dallas Cowboys had a miserable season last year, finishing an abysmal 7-10. Quarterback Dak Prescott and wide receiver CeeDee Lamb both missed significant time with injuries, but they are healthy and ready to go for this season. Prescott and Lamb have formed one of the best tandems in the league over the last half-decade, but staying healthy has been a consistent issue. However, for the first game of the season, they will be fresh and ready to go.
The Cowboys had a strong wide receiver-quarterback duo in Dallas, but they weren’t satisfied and acquired George Pickens from the Pittsburgh Steelers. Pickens is one of the most consistent receivers in the league, and Prescott will be the best quarterback he has played with in his career. The fact that Pickens thrived as he did in Pittsburgh will fill the Cowboy fan base with optimism, and he will be crucial to Dallas’ success in this game and all season long.
Dallas knows they can keep up with the Eagles offensively, and their hopes and dreams of winning the NFC East will hinge on their pass rush. Micah Parsons had a sophomore slump last season, and a dominant Dallas pass rush is no more. Dante Fowler Jr. and Parsons are consistent, but they haven’t been getting the support they need from the rest of the Dallas defense. Shutting down Barkley and Hurts is no easy task, but Dallas will need to win this game in the trenches if they hope to start off their season on a winning note.
How to Make Philadelphia Eagles vs Dallas Cowboys Picks
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