The NFL preseason week 2 odds have just been released, and this is the best opportunity to lock in your predictions for the NFL preseason week 2 lines. After getting a taste of NFL football in week 1, it is now time to look ahead at the NFL preseason odds in week 2. The best place to do so is at Sportzino. Sportzino offers NFL preseason weeks 2 lines and odds, including spreads, moneylines, and totals to make your free predictions.
2024 NFL Preseason Week 2 Odds

Moneyline:
| Favorite | Underdog |
| New England Patriots (-158) | Philadelphia Eagles (+112) |
| Baltimore Ravens (-128) | Atlanta Falcons (-109) |
| Chicago Bears (-313) | Cincinnati Bengals (+210) |
| Houston Texans (-180) | New York Giants (+128) |
| Kansas City Chiefs (-213) | Detroit Lions (+150) |
| Cleveland Browns (-150) | Minnesota Vikings (+108) |
| New York Jets (-200) | Carolina Panthers (+142) |
| Indianapolis Colts (-200) | Arizona Cardinals (+142) |
| Miami Dolphins (-138) | Washington Commanders (+100) |
| Pittsburgh Steelers (-209) | Buffalo Bills (+145) |
| Tennessee Titans (-158) | Seattle Seahawks (+112) |
| Los Angeles Rams (-128) | Los Angeles Chargers (-109) |
| Jacksonville Jaguars (-180) | Tampa Bay Buccaneers (+128) |
| Las Vegas Raiders (-334) | Dallas Cowboys (+220) |
| Denver Broncos (-334) | Green Bay Packers (+220) |
| New Orleans Saints (-150) | San Francisco 49ers (+108) |
NFL Preseason Week 2 Odds Analysis
Philadelphia Eagles at New England Patriots: Thursday, August 15th, 7 PM EST
The Eagles and Patriots both won their first game, and the superior quarterback play from the Patriots will allow New England to stay undefeated. Drake Maye and Jacoby Brissett will be in a fierce battle for QB1, and this game will go a long way in determining the week 1 starter.
Atlanta Falcons at Baltimore Ravens: Saturday, September 17th, 12 PM EST
Michael Penix Jr. will steal the spotlight here and is the reason the Falcons are only short underdogs based on the NFL preseason odds in week 2. The Ravens are dominant in the preseason, and this year will be the same story. This will be a good one.
Cincinnati Bengals at Chicago Bears: Saturday, September 17th, 1 PM EST
The Bears are massive -313 favorites based on the NFL odds preseason week 2, and will be able to swat aside the Bengals in this meaningless game. Joe Burrow will be very limited, while the Bears will be eager to get Caleb Williams as many snaps as possible before the regular season kicks off next month.
New York Giants at Houston Texans: Saturday, September 17th, 1 PM EST
The Giants and Texans both won their opening week games and will be looking to clamp down on defense in this matchup. The Giants were fortunate against the Lions, but with more Houston players set to suit up, Houston will be the team moving to 2-0.
Detroit Lions at Kansas City Chiefs: Saturday, September 17th, 4 PM EST
A rematch of the opening game of the 2023 regular season is on tap, and the NFL preseason spreads week 2 have this as one of the most exhilarating games. Patrick Mahomes is unlikely to have an impact, and the Lions’ gritty defense will allow Detroit to pull off the upset.
Minnesota Vikings at Cleveland Browns: Saturday, September 17th, 4:25 PM EST
The Vikings were treated to a strong showing from JJ McCarthy in the opening game, and they will hope their young quarterback can put another solid showing together against the Browns. The Cleveland defense is tough, but with a real quarterback battle in Minnesota, the Vikings will prevail.
Seattle Seahawks at Tennessee Titans: Saturday, September 17th, 7 PM EST
The Seahawks and Titans have been stuck in mediocrity for years, and this year will be no different. This will be an uninspiring matchup, and it wouldn’t be a surprise to see one or both teams get stuck in single digits.
Buffalo Bills at Pittsburgh Steelers: Saturday, September 17th, 7 PM EST
The Bills and Steelers scored a combined 18 points in their opening games. There is nothing to see here.
New York Jets at Carolina Panthers: Saturday, September 17th, 7 PM EST
The New York Jets are once again filled with optimism and are favorites on the NFL preseason week 2 odds despite no Aaron Rodgers under center. Take a shot with the Panthers and their +142 odds this weekend.
Washington Commanders at Miami Dolphins: Saturday, September 17th, 7 PM EST
The Commanders got a strong showing from Jayden Daniels in his first NFL action, and the number two overall pick will see increased usage this week against Miami. The Dolphins have a fragile mentality, and with nothing on the line, the Commanders will earn the victory.

Arizona Cardinals at Indianapolis Colts: Saturday, September 17th, 7 PM EST
The Indianapolis Colts are -200 favorites despite allowing 24 points last weekend. The rotation players for their defense are simply not good enough, and as soon as the starters take a seat, the Cardinals will roll full steam ahead.
Los Angeles Rams at Los Angeles Chargers: Saturday, September 17th, 7:05 PM EST
In the battle of Los Angeles, it will be the -128 Rams who prevail. The Chargers will not rush Justin Herbert back with little to play for at this stage, and their current offensive unit scored just three points with 198 yards against a crumbling Seahawks defense to open up the preseason. The Rams will win, and it will be by double digits.
Tampa Bay Buccaneers at Jacksonville Jaguars: Saturday, September 17th, 7:30 PM EST
The Buccaneers and Jaguars both enjoyed opening wins against stiff competition, but the party will end for one of these two teams this weekend. The Jaguars have the deeper quarterback room, which is usually enough in preseason play.
Dallas Cowboys at Las Vegas Raiders: Saturday, September 17th, 10 PM EST
The Raiders are -334 favorites, which is far too wide at this stage of the season. Las Vegas has high-level quarterbacks, but NFL preseason week 2 odds like this make them unplayable. It’s the Cowboys or nothing with these odds.
Green Bay Packers at Denver Broncos: Sunday, September 18th, 8 PM EST
The Broncos have several quarterbacks, including the red-hot Bo Nix, who lit it up in his NFL debut. Between Nix, Zach Wilson, and Jarrett Stidham, the Broncos are the clear favorites to win, and win big against the Packers.
New Orleans Saints at San Francisco 49ers: Sunday, September 18th, 8 PM EST
The 49ers are a top-heavy team that is hard to predict in the preseason. Better options are available on the NFL odds preseason week 2 slate.





