The final week of the NFL season is here, and it is time to make your free NFL Week 18 predictions on Sportzino.
All 32 teams are in action for what will be the final game of the year for some, but a tune-up game before the postseason for others. The NFL odds have been released, and it’s time to jump right into the NFL week 18 predictions.
Make sure you carefully analyze the odds on your sportsbook before making any predictions of your own, as that will be the difference between staying on top and falling behind in the long run.
NFL Week 18 Predictions and Picks
Game 1: Seattle Seahawks at San Francisco 49ers

Saturday, January 3rd, 8:00 PM EST
- Moneyline: Seahawks -125, 49ers -110
- Spread: Seattle Seahawks (-1.5)
- Total: 49.5 Points
The NFC West is on the line in this one, and the winner will also get a first-round bye with the #1 seed in the entire conference.
Seattle is a slight road favorite on the NFL odds, and they absolutely deserve that price tag. They have the better defense, the more consistent offense, and even though tailing Sam Darnold in a big game is scary, the Seahawks quarterback has proven he is among the best in the league with his solid play this season.
The 49ers will be a popular pick as underdogs, but the Seahawks have been the better team on both sides of the ball this year and will take the number one spot in the conference with a win.
Pick: Seattle Seahawks Moneyline -125
Game 2: Indianapolis Colts at Houston Texans

Sunday, January 4th, 1:00 PM EST
- Moneyline: Colts +375, Texans -650
- Spread: Houston Texans (-9.5)
- Total: 40.5 Points
The Texans and Colts both had strong seasons, but the Colts’ inability to close out the year has taken away some of the allure of this divisional clash.
The Texans’ defense has been the best unit in the league, and there will be very few opportunities for Philip Rivers to move the ball down the field. Houston isn’t going to take any chances on offense either, making this total of 40.5 points far too high.
Pick: Texans vs Colts Under 40.5 -120
Game 3: Baltimore Ravens at Pittsburgh Steelers

Sunday, January 4th, 8:20 PM EST
- Moneyline: Ravens -200, Steelers +140
- Spread: Baltimore Ravens (-3.5)
- Total: 40.5 Points
The Ravens made a remarkable comeback to set up this winner-take-all game to close out the regular season, and it’s a highlight of our NFL predictions for Week 18.
The Steelers are attractive home underdogs, but with a short spread and all the momentum, Baltimore is the way to go. Lamar Jackson should be back for this one, and the Ravens showed they still know how to run the ball.
Pittsburgh will be physical as usual, but their lack of offensive sparks with DK Metcalf suspended makes them hard to back. Even with the spread over a field goal, Baltimore will take no chances in what could be a blowout win to take the AFC North.
Pick: Baltimore Ravens (-3.5) -125
NFL Player Prop Predictions: Carolina Panthers at Tampa Bay Buccaneers
Saturday, January 3rd, 4:30 PM EST
- Moneyline: Panthers +115, Buccaneers -160
- Spread: Tampa Bay Buccaneers (-2.5)
- Total: 44.5 Points
The Panthers have gotten themselves in this position thanks to their commitment to running the ball. Rico Dowdle has been a major factor in their success, and he will have a big game against the Buccaneers.
He has averaged 69.66 rushing yards per game in his last 15 appearances, and there is no reason to expect his snap share to decrease in this crucial game. With a line of 52.5 rushing yards, it’s an easy over for Dowdle.
Pick: Rico Dowdle Over 52.5 Rushing Yards -125
- ALSO CATCH: NFL Week 17 Predictions

NFL Score Predictions: Los Angeles Chargers at Denver Broncos
Sunday, January 4th, 4:25 PM EST
- Moneyline: Chargers +260, Broncos -400
- Spread: Denver Broncos (-7.5)
- Total: 39.5 Points
The plus money odds on the Chargers to get on the board first offer plenty of upside. The Chargers have a strong passing attack, and will now know how to deal with a dangerous defensive line after facing the Texans last week.
Denver has waited until the second half to get their offense going in recent weeks, and another slow start from the home team can be expected.
Pick: First team to score, Los Angeles Chargers +140
NFL Moneyline Predictions: New York Jets at Buffalo Bills
Sunday, January 4th, 4:25 PM EST
- Moneyline: Jets +285, Bills -450
- Spread: Buffalo Bills (-7.5)
- Total: 39.5 Points
This isn’t a great set of live sports odds for the Bills, but with seeding on the line, they will smash the New York Jets.
This is almost certainly the final game in Highmark Stadium, and the Bills Mafia will be sent home with smiles on their faces. New York’s defense is abysmal; they don’t have a legitimate quarterback, and there will be one-way traffic on the field this Sunday.
Pick: Buffalo Bills Moneyline -450
NFL Against the Spread Predictions: Washington Commanders at Philadelphia Eagles
Sunday, January 4th, 4:25 PM EST
- Moneyline: Commanders +260, Eagles -400
- Spread: Philadelphia Eagles (-8.5)
- Total: 41.5 Points
The Eagles will have a chance to tune up their offense against a struggling Commanders defense this week. They are desperate to build some momentum heading into the playoffs, and they will do exactly that against a helpless Washington side.
Josh Johnson is a third-string quarterback with minimal upside, and anything short of a double-digit massacre for the Eagles would be a real surprise.
Pick: Philadelphia Eagles (-8.5) -120





