The college football odds for week 1 have been released, with several intriguing matchups scheduled to start off the season. A fast start to the season can propel teams into the playoffs, and the top 25 teams must avoid an early setback. The NCAAF odds can be quite wide, but the college football point spreads to ensure that odds for both teams are available at reasonable lines.
There is one clear place to make your free college football point spread picks, and that is Sportzino. Sportzino offers college football odds and college football lines for all the major week 1 matchups and has the standard moneyline and Over/Under lines, in addition to college football spreads.
College Football Week 1 Odds
Hundreds of teams will kick off their season this week, and a few matchups stand out as the can’t miss games of the week. The NCAA football odds include moneylines, totals, and college football spreads.
| Matchup | Spread | Moneyline | Over/Under |
| Florida State at Georgia Tech | Florida State -11 (-118) | FSU -500/GT +300 | 55.5 |
| Temple at Oklahoma | Oklahoma -42.5 (-119) | Temple +1100 | 59.5 |
| Clemson at Georgia | Georgia -14.5 (-109) | GU -750/CT +400 | 49.5 |
| Virginia Tech at Vanderbilt | Virginia Tech -13.5 (-123) | VT -600/VAN +350 | 54 |
| Penn State at West Virginia | Penn State -10 (-116) | PENN -434/ WV +275 | 51 |
| North Dakota State at Colorado | Colorado -9 (-119) | COL -367/NDS +240 | 58.5 |
| Coastal Carolina at Jacksonville State | Jacksonville State -3.5 (-113) | JS -180/CC +128 | 56.5 |
| Colorado State at Texas | Texas -35.5 (-113) | CS +1100 | 58.5 |
| Akron at Ohio State | Ohio State -50.5 (-117) | Akron +25000 | 58.5 |
| Old Dominion at South Carolina | South Carolina -20 (-120) | SC -1500/OD +600 | 54.5 |
| Boise State at Georgia Southern | Boise State -12.5 (-116) | BS -500/GS +300 | 57.5 |
| Notre Dame at Texas A&M | Texas A&M -2.5 (-117) | TAM -150/ND +108 | 46.5 |
| Fresno State at Michigan | Michigan -21 (-123) | MICH -2000/FS +700 | 48.5 |
| USC at LSU | LSU -6 (-118) | LSU -240/USC +166 | 63.5 |
College Football Week 1 Odds Analysis
Clemson at Georgia
- Spread: Clemson +14.5, Georgia -14.5
- Moneyline: Clemson +400, Georgia -750
- Over/Under: 49.5 Points
Clemson and Georgia both have playoff aspirations this season, with the Georgia Bulldogs coming in as the favorites to win the college football championship. Carson Beck is returning as the quarterback for Georgia, after putting together a solid season last year. Beck will need to ignite the Georgia offense, which lost several starters in the NFL draft. Georgia went 13-1 last season, and with Alabama scheduled in a few weeks, they cannot afford to drop this matchup. Clemson quarterback Cade Klubnik will have a hungry Georgia defensive line chasing him down and may come into this matchup nervous after rumors of Trent Pearman coming for his starting job. A desperate Clemson team coming up against a ruthless Georgia squad will see the Bulldogs cruise to a big win to start their campaign.
Pick: Georgia -14.5 (-109)
Notre Dame at Texas A&M
- Spread: Notre Dame +2.5, Texas A&M -2.5
- Moneyline: Notre Dame +108, Texas A&M -150
- Over/Under: 46.5 Points
Notre Dame and Texas A&M is a fascinating week 1 matchup, as an early loss will severely dampen any playoff hopes for both of these teams. Notre Dame is strong both in the air and on the ground and will be looking to improve on their 10-3 showing last season. For Texas A&M, they will need to dig deep to deliver a win for their home crowd. It isn’t surprising to see Texas A&M come in as the favorites, but a measly 2.5 college football point spread isn’t enough points to look the other direction. The student section will be loud for Texas A&M, and their home crowd will push them to win by three or more points.
Pick: Texas A&M -2.5 and Moneyline -150
USC at LSU
- Spread: USC +6, LSU -6
- Moneyline: USC +166, LSU -240
- Over/Under: 63.5 Points
If you are a fan of high-quality defensive football, this is not the game for you. USC and LSU both have built top-heavy offenses while neglecting their defensive players going the other way. The defenses will do their best to slow down these high-octane offenses, but with very few punts expected, the 63.5 point total is still too low. Both of these teams are capable of putting up 40+ points and know that will be needed to secure a victory. One of these two offenses will find their groove, and the other will push the total the rest of the way over this line.
Pick: Over 63.5 Points -117
College Football Week 1 Odds FAQ
When do College Football Week 1 games begin?
College football week 1 games begin on Saturday, August 24th, at 12 PM EST. The first matchup is between Florida State and Georgia Tech, with Florida State coming in as 11 point favorites on the college football odds. There will be dozens of games taking place during NCAAF week 1, with the final game between Boston College and Florida State wrapping up on Monday, August 26th at 7:30 PM EST
What is the Best Game of the Week?
The best game of the week will take place between the Georgia Bulldogs and the Clemson State Tigers. Georgia is coming into the game as the number one ranked team in the country, with Clemson not far behind at 14th. Clemson dominated the late 2010s, reaching the college football playoffs in six straight seasons. Meanwhile, Georgia won back-to-back college football championships in 2021 and 2022 and is once again favored to lift the 2024 college football championship.
Other contenders for the best game of the week are the matchups between ranked teams Notre Dame and Texas A&M, and the Sunday night matchup between USC and LSU. USC and LSU are two high octane offenses, with an Over/Under of 63.5 points. It will be a high scoring game and will be the most entertaining game of the week.






