College football season is rolling through conference schedules, and with college football predictions Week 9 ahead, Sportzino’s free sportsbook and live sports odds are here to break it all down for you.
Last week featured upsets and fireworks, with Miami falling to unranked Louisville at home, Vanderbilt continuing its ascension against LSU, and the Fighting Irish holding off their old foe in South Bend. Breaking down this week’s American football odds, there are plenty more exciting NCAAF odds to unpack.
With a trio of ranked verse-ranked games on this week’s slate, you don’t want to miss any of the action. Read on for our college football week 9 odds and predictions.
College Football Week 9 Odds
| Matchup | Spread | Moneyline | Over/Under |
| South Florida vs. Memphis | South Florida -4.5 (-105) | South Florida -190/Memphis +130 | 65.5 (-115) |
| UCLA vs. Indiana | Indiana -24.5 (-115) | UCLA +900/Indiana OTB | 54.5 (-120) |
| Syracuse vs. Georgia Tech | Georgia Tech -17.5 (-120) | Syracuse +475/Georgia Tech -1,100 | 55.5 (-110) |
| Virginia vs. North Carolina | Virginia -9.5 (-130) | Virginia -425/North Carolina +265 | 51.5 (-130) |
| Ole Miss vs. Oklahoma | Oklahoma -4.5 (-120) | Ole Miss +140/Oklahoma -210 | 52.5 (-120) |
| Illinois vs. Washington | Washington -4.5 (-120) | Illinois +150/Washington -225 | 55.5 (-110) |
| Alabama vs. South Carolina | Alabama -13.5 (-120) | Alabama -650/South Carolina +350 | 47.5 (-120) |
| Missouri vs. Vanderbilt | Vanderbilt -2.5 (-140) | Missouri +125/Vanderbilt -180 | 52.5 (-120) |
| BYU vs. Iowa State | Iowa State -2.5 (-135) | BYU +110/Iowa State -160 | 49.5 (-115) |
| Oklahoma State vs. Texas Tech | Texas Tech -38.5 (-125) | Oklahoma State +1,000/Texas Tech OTB | 56.5 (-125) |
| Baylor vs. Cincinnati | Cincinnati -6.5 (-110) | Baylor +155/Cincinnati -230 | 56.5 (-125) |
| Texas vs. Mississippi State | Texas -6.5 (-120) | Texas -275/Mississippi State +180 | 46.5 (-120) |
| Stanford vs. Miami (FL) | Miami -30.5 (-120) | Stanford +900/Miami OTB | 48.5 (-115) |
| Wisconsin vs. Oregon | Oregon -33.5 (-130) | Wisconsin +1,000/Oregon OTB | 45.5 (-115) |
| Texas A&M vs. LSU | Texas A&M -2.5 (-125) | Texas A&M -145/LSU +100 | 49.5 (-125) |
| Michigan vs. Michigan State | Michigan -14.5 (-110) | Michigan -800/Michigan State +400 | 48.5 (-120) |
| Boston College vs. Louisville | Louisville -24.5 (-115) | Boston College +800/Louisville OTB | 54.5 (-120) |
College Football Week 9 Odds Analysis
(No. 15) Missouri at (No. 10) Vanderbilt
- Spread: Vanderbilt -2.5 (-140)
- Moneyline: Missouri +125/Vanderbilt -180
- Over/Under: 52.5 (-120)
- Time: Saturday, October 25 at 3:30 p.m. ET
With a slim spread to cover a week ago, Vanderbilt welcomed the LSU Tigers into Nashville and promptly won by a touchdown to secure bowl eligibility for the 2025 season. It was the latest mark in an astonishing Commodores’ rise, but don’t think the perennial SEC bottom-feeder is done.
With the Missouri Tigers coming in this week, Vandy has yet again been given a slight, 2.5-point line to cover. Compared to the pressure of last week’s matchup, the clash with Mizzou is considerably more straightforward. Don’t expect Vanderbilt to flinch now.
Pick: Vanderbilt -2.5 (-140)
(NR) Stanford at (No. 9) Miami
- Spread: Miami -30.5 (-120)
- Moneyline: Stanford +900/Miami OTB
- Over/Under: 48.5 (-115)
- Time: Saturday, October 25 at 7:00 p.m. ET
Last weekend was an absolute disaster for the Miami Hurricanes, who were upset by an unranked Louisville Cardinals team, saw quarterback Carson Beck blame teammates, and then fell from No. 2 to No. 9 in the country. It’s the type of loss that could derail a team’s season, and so the urgency in South Beach will be high.
Luckily for Beck and company, they’ve got a perfect bounce-back spot. With non-ranked Stanford coming all the way across the country to Miami, the Hurricanes are poised to take out a week of frustration on a woefully overmatched opponent. Miami has college football playoff aspirations, and it’ll put its credentials on display to put a humiliating loss behind it.
Pick: Miami -30.5 (-120)
(NR) Wisconsin at (No. 6) Oregon
- Spread: Oregon -33.5 (-130)
- Moneyline: Wisconsin +1,000/Oregon OTB
- Over/Under: 45.5 (-115)
- Time: Saturday, October 25 at 7:00 p.m. ET
Not only did Wisconsin fail to cover receiving a massive sum of points last week against No. 1 Ohio State—at home—but it lost in such brutal fashion that Camp Randall Stadium turned toxic, and so did the mood around the program.
Now, the Badgers have to head up to Eugene to face No. 6 Oregon and are again getting a swath of points. But, after they failed to muster any offense in a shutout last weekend, the season is about to really get away from them. The Ducks, like the Buckeyes a week ago, should steamroll a Wisconsin team that is completely lost at this point in the season.
Pick: Oregon -33.5 (-130)
- You Might Also Like: College Football Prediction Week 8
College Football Week 9 Odds FAQ
When do the College Football Week 9 games begin?
The first college football game of Week 9 is on Tuesday, October 21, at 7:00 p.m. ET, as Kennesaw State heads to South Beach to face Florida International. The first college football game of Week 8, featuring a team currently ranked in the top 25 of the college football rankings, comes on Saturday at 12:00 p.m. ET, with a slate of games headlined by UCLA traveling to No. 2 Indiana.
What is the Best Game this week?
There are a few candidates for the best game of the week, but our NCAAF prediction to get that title has to go to the classic college football rivalry between No. 25 Michigan and unranked Michigan State. A heated rivalry promises great drama, despite both schools’ middling seasons. Another exhilarating matchup is a clash of SEC upstarts, with No. 10 Vanderbilt hosting No. 15 Missouri.
How to Make College Football Week 9 Picks
Ready to make picks on the college football Week 9 slate this weekend? Make sure to head over to Sportzino.com, where you can find every college football game on the schedule this week, and so much more!
